West Brom boss Gary Megson is facing an anxious wait to see if defensive lynchpin Darren Moore will be fit. Moore has missed the last five games with a troublesome calf strain. Striker Jason Roberts is a definite absentee after breaking his foot for the third time this season.
West Brom (from): Hoult, Clement, Sigurdsson, Butler, Gilchrist, Balis, Chambers, McInnes, Johnson, Dichio, Dobie, Fox, Taylor, Jordao, Lyttle, Adamson, Moore.
Fulham's Sean Davis will have a final fitness check on a bruised thigh while Lee Clark (calf) is definitely out. Sylvain Legwinski is back in the squad after completing a suspension.
Fulham (from): Van der Sar, Brevett, Finnan, Ouaddou, Melville, Goma, Collins, Legwinski, Knight, Malbranque, Davis, Taylor, Marlet, Saha, Hayles, Boa Morte.
MOST SIGNIFICANT STATS
West Brom - the only club outside the Premiership still in the competition - are aiming to repeat history. The Baggies, who qualified for the Quarter-finals for the first time in 20 years, are the only club ever to win the Cup and gain promotion in the same season - 1930/31.
Fulham, 12 places above their Midlands opponents on the League ladder, have never won the Cup but were runners-up in 1974/75 when they lost 2-0 to West Ham in the final. That was also the last time they qualified for the Quarter-finals.
Albion lifted the Cup for the fifth time in 1967/68. They are aiming to reach the semi-finals for the 20th time - Fulham their 6th.
WBA hold a 100% FA Cup record against Fulham with three wins out of three. The most recent was in the Fourth Round in 1969. They have never met beyond Round Four.
Albion's last win in the Quarter-finals was 2-0 at home to Coventry in 1981/82, while Fulham's was 0-1 away to Carlisle in 1974/75.
West Brom have had the more impressive run to the last eight with straight victories over Sunderland (away), Leicester (home) and Cheltenham (home). Fulham needed a replay to knock out Wycombe and have subsequently won away to York and Walsall.
Fulham are three goals away from scoring 150 in away ties.
Albion have not lost at home in the F.A. Cup Sixth Round since 1884/85 when Blackburn won 2-0.
The last two times that Fulham reached the semis they won Sixth Round games away from home.
When the teams met in 1968/69 Fulham had recently sacked their manager Bobby Robson - the former West Bromwich Albion player and now in charge at Newcastle.
Total: 64: West Brom wins 32, Fulham wins 19, draws 13
WEST BROMWICH ALBION
Current League position, 3rd D1
10 HOME MATCHES WITHOUT DEFEAT - 8 D1, 2 FAC [8 wins, 2 draws]
Won 10 of last 14
1 draw in last 11
2 defeats in last 5
Failed to score in 2 of last 5 games
9 clean sheets in last 12
ADDITIONAL BAGGIES NOTES
When Albion defeated Fulham in 1968/69 they then knocked out both Arsenal and Chelsea before losing in the semis to Leicester.
Only three seasons ago, West Brom were a Division higher than Second Division Fulham. But Premiership new-boys Fulham start as clear favourites, having spent heavily since then. £30 million has been spent this season compared with just £2 million by Megson's Baggies.
West Brom last won the Cup in 1968, when Albion favourite Jeff Astle scored the winner in the final. Astle sadly passed away earlier this year, aged 59.
Albion's highly-rated full-back Neil Clement began his career with Fulham's great rivals Chelsea. He is the club's top scorer in this competition with two - both penalties - and will be extra keen to add to his tally in this one.
A single goal could well be enough to take either team through to the last four. Since they won 2-1 at Sunderland in round three, seven of West Brom's next 10 games finished 1-0 - and on six of those occasions, Megson's team ran out winners.
Stadium Name: The Hawthorns
Capacity: 27,200 all seated
Address: Halfords Lane, West Bromwich, B71 4LF
Main Telephone No: 0121-525-8888
Nickname: The Baggies
Pitch Size: 115 x 75 yards
Club Sponsors: West Bromwich Building Society
Home Colours: Navy & White
Away Colours: Green & Yellow
Kit Makers: Patrick
Official Web Site: www.wba.co.uk
Current League position 11th PREM
LOST LAST 4 - all Prem
GONE 6 SINCE A DRAW
COMPLETED 5 GAMES SINCE A CLEAN SHEET
2 wins in last 8
1 draw in last 9
Lost 5 of last 7
Failed to score in 3 of the last 8 matches
3 clean sheets in last 9
Potential Career Milestones
Barry HAYLES needs a double strike to register 50 goals for Fulham
If he plays, Paul TROLLOPE will be making his 100th appearance for the Cottagers
ADDITIONAL COTTAGERS NOTES
Premiership Fulham have been drawn away to a lower division side in each of the four rounds of this season's competition.
Cottagers striker Barry Hayles - who has two goals to his name in this season's competition - is a former team-mate of West Brom's leading scorer Jason Roberts. The pair formed a formidable strike partnership at Bristol Rovers in 1998.
Fulham's only FA Cup Final appearance, the 2-0 defeat to West Ham in 1975, did not feature the traditional singing of 'Abide With Me'. Supporters of both clubs provided their own entertainment to fill the void.
MAN IN THE MIDDLE, NEALE BARRY, Roxby, North Lincolnshire.