Slaviša Jokanović will be without Tomas Kalas for the visit of Bristol City to Craven Cottage on Saturday.
The on-loan defender has joined two previous absentees on the treatment table, but Sone Aluko and Chris Martin will be available following injury and EFL Cup ineligibility, respectively.
“We lost Ryan Fredericks, we lost Floyd Ayité, and Tomas Kalas,” Jokanović explained. “They’re not going to be available for this week in front of us.
“We won’t have the opportunity to use these three players. Sone Aluko is okay, and the other players are ready for the fight.”
Fulham’s Head Coach made sweeping changes to his starting XI when the Robins triumphed in the cup on Wednesday, and he confirmed there will be further alterations at the weekend.
“We’re going to make changes,” he stated. “For me it was the perfect moment to use different players, like I used in the two games before in the cup.
“I put people in the field who I believed could win the game, and this is our intention for all the games. And yes, now we’re going to try with some different people, and try to win the game, something we didn’t do before.”
Tickets for the game are available to purchase on General Sale, priced from £25 for adults and £15 for juniors, with a £5 increase on matchday.