Fulham gained their second Premiership win of the season as two first-half goals from Steed Malbranque saw off Southampton.
Fulham were held by Ipswich Town at a rain-soaked Craven Cottage on a bad day for Luis Boa Morte; who missed a penalty and was later sent off.
Fulham were defeated 2-0 by high-flying and unbeaten Aston Villa at Villa Park in Sunday's early kick-off.
Undaunted by the recent superiority of their West London rivals Chelsea, Jean Tigana's enterprising Fulham side not only won a point but also made one at Craven Cottage.
Leicester manager Peter Taylor had the consolation of seeing his side keep a clean sheet for the first time in six Barclaycard Premiership matches.
Despite Steed Malbranque's equaliser, Fulham were undone by two late goals against Arsenal at Craven Cottage.
An own goal by Andy Melville prevented Jean Tigana celebrating his 50th league game in charge of Fulham with a win. Luis Boa Morte quickly equalised but the Whites couldn't find a winner that their impressive performance deserved.
Fulham failed to capitalise on an under-strength Derby County side in a game that saw the visitors defend resolutely and leave Craven Cottage with a point.
Fulham confirmed their Premiership credentials as goals from Barry Hayles and Louis Saha earned them a pulsating 2-0 victory over Sunderland at Craven Cottage.
It was gripping and ground-breaking, but ultimately for Fulham their first match in the Premiership ended in grief.